Judge Bianco was appointed as a United States Circuit Judge for the Second Circuit by President Donald J. Trump on May 13, 2019, and entered service on May 17, 2019. Prior to his appointment as a United States Circuit Judge, Judge Bianco served as a United States District Court Judge in the Eastern District of New York. Judge Bianco was appointed as a United States District Judge in the Eastern District of New York by President George W. Bush on January 3, 2006, and entered service on that same date.

Judge Bianco obtained his B.A., magna cum laude, at Georgetown University in 1988 and received his law degree in 1991 from Columbia Law School, where he was a Kent Scholar and a member of the Law Review. From 1992-1993, he served as a law clerk for the Honorable Peter K. Leisure, United States District Judge for the Southern District of New York. For a period of time both before and after that clerkship, he worked as a litigation associate at Simpson Thacher & Bartlett LLP.

From 1994-2003, Judge Bianco served as an Assistant United States Attorney in the Southern District of New York, where he became Deputy Chief and then Chief of the Organized Crime and Terrorism Unit. In 2003, Judge Bianco left the Department of Justice and became Counsel with Debevoise & Plimpton LLP in its Litigation Department.

In 2004, Judge Bianco returned to the Department of Justice and was appointed as a Deputy Assistant Attorney General in the Criminal Division in Washington, D.C., where he supervised the Counterterrorism Section, the Fraud Section, the Appellate Section, and the Capital Case Unit. He occupied that position until his appointment to the bench.

Judge Bianco has taught courses at Fordham Law School, Hofstra Law School, and Touro Law Center. He currently teaches at St. John's University School of Law.